Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease affecting 16 million Americans.1 While multiple factors are associated with COPD (e.g., occupational dust, air pollution, genetic factors), one of the leading causes is smoking.2

Over time, smoking destroys the air sacs, damages delicate lung tissue, and impairs the cilia in the lungs from successfully clearing mucus. All of this can lead to recurring infections, shortness of breath, wheezing, and other serious respiratory health issues.

Understanding the relationship between smoking and COPD, as well as exploring safer alternatives and ways to quit, is crucial for anyone at risk or living with this condition.

COPD and Smoking: What Are the Dangers of Smoking with a Respiratory Disease?

As noted above, smoking is the primary risk factor for COPD.3 Any amount of smoking increases the risk of developing COPD, but heavier and longer smoking increases the risk further. If you have COPD and you smoke, the constant irritation and infection of your lungs can trigger a COPD flare-up. Flare-ups can also result from exposure to secondhand smoke that irritates your lungs and makes chronic symptoms worse.4

A COPD flare-up might include:

Because smoking deprives your lungs and other essential organs of oxygen, and your respiratory condition is already constricting your airways, smoking and COPD can be a dangerous combination that may result in frequent flare-ups, extensive treatment, and recurring hospitalizations.4

Can Smoking Cause COPD?

Yes, smoking is one of the leading causes of COPD. The harmful chemicals in tobacco smoke damage the air sacs in the lungs, leading to decreased oxygen exchange. Cigarette smoke irritates the airways, leading to inflammation and damaging the delicate lung tissue, ultimately reducing lung function. Over time, this damage causes airflow obstruction and the hallmark symptoms of COPD.

It’s important to note that the risk of COPD is cumulative. The longer you smoke and the more cigarettes you consume, the higher your likelihood of developing the disease.5 Quitting can slow progression, improving symptoms and outcomes, but it may not fully reverse structural lung damage already present.

Can Vaping Cause COPD?

While vaping is often marketed as a safer alternative to smoking, research indicates that e-cigarettes are not harmless. The chemicals in vaping liquids, including nicotine, flavorings, and other toxins, can irritate the lungs and lead to inflammation.

Observational evidence suggests that long-term vaping may be associated with developing COPD or worsening existing lung conditions. For people with COPD, vaping or the use of e-cigarettes is not a risk-free alternative and should be approached with caution.

Should I Quit Smoking?

Though you can’t reverse lung damage, quitting can impact how the disease progresses. Here are just a few effects quitting can have on your well-being and quality of life: 

The faster you quit, the greater your chance of slowing the progression of your condition. By quitting, your individual treatment may become more effective, although you may require additional COPD treatment methods, including: 

What’s the best way to quit smoking if I have COPD?

If you have COPD, quitting is the single most effective way to slow its progression and improve your quality of life. Here are a few strategies:

You don’t have to pick just one. Combining multiple strategies often yields the best results. 

Frequently Asked Questions: COPD & Smoking

SmartVest is Here to Make Breathing Easier

If you’re living with a chronic lung condition, you’re not alone. Take proactive steps to breathe easier and get back to life. SmartVest provides a proven airway clearance therapy to help clear mucus from the lungs. 

Request an informational packet to understand how this approach works and if it’s right for you. 

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Resources

  1. United States Centers for Disease Control and Prevention. (2024.) “COPD.” 
  2. World Health Organization. (2023.) “Smoking is the leading cause of chronic obstructive pulmonary disease.
  3. American Lung Association. (2025.) “10 of the Worst Diseases Smoking Causes.” 
  4. United States Centers for Disease Control and Prevention. (2025.) “Smoking and COPD.” 
  5. National Library of Medicine. (2018.) “Factors associated with current smoking in COPD patients: A cross-sectional study from the Eastern Black Sea region of Turkey.” 
  6. Medical News Today. (2025.) “What Happens After You Quit Smoking?” 
  7. National Library of Medicine. (2025.) “Association of electronic cigarette use and risk of COPD: a systematic review and meta-analysis.” 

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