
Flare-ups and acute exacerbations—what exactly do these terms mean? Suppose you or a loved one has a chronic lung condition like bronchiectasis or COPD (chronic obstructive pulmonary disease). In that case, you may have heard your clinician use these terms interchangeably, or maybe you’ve required hospitalization because of them.
But what is a flare-up? More specifically, how do you know if you’re experiencing one and what should you do next?
In this article, we’ll explore the definition of a flare-up (i.e., acute exacerbation), its causes, and how to manage symptoms to avoid triggering one.
Definitions
- Flare-Up: A sudden worsening of disease or condition symptoms.¹
- Exacerbation: An increase in the severity of a disease or its signs and symptoms.² Regarding pulmonary diseases like COPD, an acute exacerbation is a sudden worsening of airway function and respiratory symptoms.³
Are Flare-Ups and Acute Exacerbations the Same Thing?

Both terms describe the same reaction our bodies have to triggers; the only real difference is that one (i.e., flare-up) gets used more frequently. As this is the case, we will also use these terms interchangeably in the sections below.
Chronic Conditions & Acute Exacerbations

Acute exacerbations are sudden and severe worsening of symptoms associated with your chronic condition. For example, common symptoms of bronchiectasis and COPD include:
- Shortness of breath
- Chronic cough
- Wheezing
- Mucus buildup
- Respiratory infections
Patients will experience these symptoms individually and regularly. However, a sudden flare-up of symptoms (i.e., severe shortness of breath that makes it difficult to breathe and receive oxygen or exhale CO2) can create life-threatening scenarios where patients may require hospitalization.
These exacerbations can be triggered by a variety of factors, including:
-
-
- Mucus buildup
- Respiratory infection
- Environmental irritants
- Pollutants
- Stress4
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Asthma, for example, can be triggered by allergens such as pollen or pet dander, while COPD can be triggered by cigarette smoke or air pollution exposure. On the other hand, bronchiectasis, a condition that damages the lungs and airways, making it difficult to clear mucus out of the lungs, is often triggered by mucus buildup. Therefore, working closely with your healthcare team to identify your triggers and developing a management plan to prevent acute exacerbations is essential.
Recognizing the Signs and Symptoms

Nevertheless, common flare-up signs may include sudden shortness of breath, chest tightness, coughing, wheezing, or difficulty breathing. You may also experience extreme fatigue, dizziness (due to low oxygen), and other symptoms.
Again, working with your healthcare team can help you identify symptoms, triggers, and an action plan to be prepared if your condition worsens.
What to Do When You Experience a Flare Up

Your healthcare provider may adjust your treatment plan or prescribe additional medications to manage the exacerbation. They may also recommend lifestyle changes or refer you to a specialist for further evaluation and treatment. Early intervention is critical to managing chronic conditions and preventing acute exacerbations.
Preventing a Flare Up

Monitoring symptoms regularly and communicating any changes to a healthcare provider is also important. By taking an active role in your healthcare journey, you can reduce the risk of acute exacerbations and improve your overall quality of life.
SmartVest Airway Clearance System

To learn more about SmartVest and Clearway, request an informational packet today! We also invite you to talk to one of our patient care advocates about getting started with SmartVest. They can walk you through your options, answer your questions, and help you take the next step in your airway clearance journey.
Resources
[1] Merriam-Webster Dictionary. “Flare Up.” Retrieved from https://www.merriam-webster.com/dictionary/flare-up
[2] RxList. “Definition of Exacerbation.” Retrieved from https://www.rxlist.com/exacerbation/definition.htm
[3] National Library of Medicine. “Acute Exacerbations and Respiratory Failure in Chronic Obstructive Pulmonary Disease.” Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645331/
[4] American Lung Association. “Coping with COPD and Anxiety.” Received from https://www.lung.org/blog/coping-with-copd-and-anxiety
